Applications of the multi-omic study of the microbiota to the development of innovative biotechnological solutions in the health area.
μBiomics (microBiomics) proposes the design, development, and implementation of a multi-meta-omic strategy that allows characterizing, at a level of detail never done before and in a completely new way, the role of the microbiota in different pathological processes (digestive, autoimmune, oncological), as well as its contribution to the response, in terms of efficacy and safety, of patients to different clinical/therapeutic interventions. From an experimental point of view, microbiota samples of different origins, coming from patients, will be analyzed using a combination of meta-omic technologies. These techniques will generate a huge amount of data that will be integrated, not only at the omic level but with other clinical data, using bioinformatic tools.
The final objective of the project is to identify bacterial communities, and enzymatic activities associated with them, that may be useful for the design of biotechnology-based therapeutic strategies.
NUCAPS joins the main public and private hospitals and scientific research centers and teams in Navarra, using the most advanced technologies (nanotechnology, Big Data, Machine Learning and five omic technologies: 16S, metagenomics, metatranscriptomics, metaproteomics and metametabolomics) to generate and analyze close to a Petabyte of data to provide an effective response and create therapies based on the knowledge generated for diseases related to the microbiota in order to improve the health and quality of life of patients with these digestive and autoimmune diseases and oncology, which currently do not have adequate clinical solutions and treatments for their diseases.
It will contribute significantly to the intelligent specialization of Navarra in the area of Biotechnology applied to health challenges.
- Title: Applications of the multi-omic study of the microbiota to the development of innovative biotechnological solutions in the health area
- Identification number: 2021.059
- Execution Period: April 2021 – December 2023
- Entity / s executing the project: Foundation for Applied Medical Research (FIMA), Clínica Universidad de Navarra (CUN), Complejo Hospitalario de Navarra (CHN), Fundación Miguel Servet (FMS), University of Navarra (CIMA LAB Diagnostics, Nutrition Research Center), ADITECH, NUCAPS and National Center for Food Technology and Safety (CNTA).
The project has been approved and financed by the Government of Navarra and is an R&D project considered strategic and is part of the SIBERIA III Challenge. Innovative Solutions in Biotechnology for Energy, Health Challenges, Industry and Agri-food, having obtained the best technical score of all those presented.