Applications of the multi-omic study of the microbiota to develop innovative biotechnological solutions in the area of health.
μBiomics (microBiomics) proposes the design, development, and implementation of a multi-meta-omics strategy that allows characterizing, at a level of detail never done before and in a completely new way, the role of the microbiota in different pathological processes (digestive, autoimmune, oncological), as well as their contribution to the response, in terms of efficacy and safety, of patients to different clinical/therapeutic interventions. From an experimental point of view, microbiota samples of different origins from patients will be analyzed using a combination of meta-omics technologies. These techniques will generate a huge amount of data that will be integrated, not only at the omic level but with other clinical data, using bioinformatics tools.
The ultimate goal of the project is to identify bacterial communities, and enzymatic activities associated with them, that may be useful for the design of biotechnological-based therapeutic strategies.
NUCAPS joins the main hospital centers and scientific research centers and teams in Navarra, public and private, using the most advanced technologies (nanotechnology, Big Data, Machine Learning, and five omic technologies: 16S, metagenomics, metatranscriptomics, metaproteomics, and metametabolomics) to generate and analyze close to a Petabyte of data to give an effective response and create therapies based on the knowledge generated for diseases related to the microbiota in order to improve the health and quality of life of patients with these digestive, autoimmune pathologies and oncology, which currently do not have clinical solutions and adequate treatments for their diseases.
It will contribute significantly to the intelligent specialization of Navarra in the area of Biotechnology applied to health challenges.
- Title: Applications of the multi-omic study of the microbiota to the development of innovative biotechnological solutions in the area of health
- Identification number: 2021.059
- Execution Period: April 2021 – December 2023
- Executing entity/ies of the project: Foundation for Applied Medical Research (FIMA), Clínica Universidad de Navarra (CUN), Complejo Hospitalario de Navarra (CHN), Miguel Servet Foundation (FMS), University of Navarra (CIMA LAB Diagnostics, Nutrition Research Center), ADITECH, NUCAPS and the National Center for Technology and Food Safety (CNTA).
The project has been approved and financed by the Government of Navarra, it is an R&D project considered to be strategic and it falls within the SIBERIA III Challenge. Innovative Solutions in Biotechnology for Energy, Health Challenges, Industry, and Agri-food, having obtained the best technical score of all those presented.